|Vetoryl Capsules 30mg 30 Count Box
What is Cushing’s syndrome?
Cushing’s syndrome occurs in dogs with high levels of the hormone cortisol. Cortisol normally gets released into the bloodstream at times of stress to prepare the body for a fight or flight response. In dogs with Cushing’s syndrome, the level of cortisol released is excessive and, if left untreated, becomes incapacitating. There are two types of Cushing's syndromes pituitary-dependent and adrenal-dependent.
What are the treatment options for dogs with Cushing’s syndrome?
If it can be determined that there is a tumor of the adrenal gland, surgical removal of the tumor may be an option, although the risks of this procedure can be high. However, it is not usually possible to remove pituitary gland tumors (the most frequent cause of Cushing’s syndrome).
The alternative to surgery is medical management. Vetoryl is the only licensed treatment available for both pituitary-dependent hyperadrenocorticism (PDH) and adrenal-dependent hyperadrenocorticism (ADH) in the United States and Europe. Vetoryl Capsules contain the active ingredient trilostane. Although the daily administration of Vetoryl does not offer a medical cure for Cushing’s syndrome, it may allow the disease to be managed successfully, enhancing the dog’s vitality and quality of life.
What are Vetoryl capsules and how do they work?
Vetoryl capsules contain the active ingredient trilostane. Trilostane blocks the excessive production of cortisol by reversibly inhibiting the action of the enzyme 3-ß hydroxysteroid dehydrogenase. While treatment with trilostane significantly reduces serum cortisol concentrations, it has not been found to reduce aldosterone significantly.
Vetoryl capsules should be administered orally once daily in the morning with food. Administration with food will significantly increase the rate and extent of absorption of Vetoryl. Starting dose will be determined by your veterinarian.